您目前的位置: 首页 » 师资队伍 » 教授、研究员 » 正文

刘寿​平

刘寿平,男,博士,现任广州医科大学药学院特聘教授,药物化学专业博士生导师。刘寿平博士毕业于南京理工大学,硕士毕业于中国药科大学,本科毕业于江西师范大学。刘博士在任职广州医科大学之前,在新加坡眼科研究所工作了将近15年之久,分别任研究员,高级研究员和主任研究员。此前,刘博士还在新加坡国立大学和中国科学院上海有机化学研究所做博士后研究。

刘教授的主要研究方向:抗感染性药物的研究、开发和应用;呼吸疾病的药物研发;天然产物的半合成、全合成及其药用开发。以通讯作者或者主要作者,刘教授的研究工作发表在Journal of Medicinal Chemistry、European Journal of Medicinal Chemistry、Journal of Biological Chemistry、 Biochemistry等学术刊物上。到目前为止, 刘教授已申请了多项发明专利,主持了各类新加坡新药基金181万新元(相当于900万元人民币),现在主持广州医科大学高水平大学建设人才启动项目(2018-2023),刘教授共发表了50多篇国际学术论文。

代表性论文:

  1. Lin S, Sin WLW, Koh JJ, Lim F, Wang L, Cao D, Beuerman RW, Ren L, Liu S.* Semisynthesis and Biological Evaluation of Xanthone Amphiphilics as Selective, Highly Potent Antifungal Agents to Combat Fungal Resistance, J Med Chem. 2017 Dec 28;60(24):10135-10150. (* Corresponding author)  

  2. Lin, Shuimu; Koh, Jun-Jie; Aung, Thet Tun; Sin, Wan Ling Wendy; Lim, Fanghui; Wang, Lin; Lakshminarayanan, Rajamani; Zhou, Lei; Tan, Donald T. H.; Cao, Derong; Beuerman, Roger W.; Ren, Li; Liu, Shouping*, Semisynthetic Flavone-Derived Antimicrobials with Therapeutic Potential against Methicillin-Resistant Staphylococcus aureus (MRSA), J. Med. Chem. 2017, Jul 27; 60(14):6152-6165.

  3. Lin, Shuimu; Koh, Jun-Jie; Aung, Thet Tun ; Lim, Fanghui; Li, Jianguo; Zou, Hanxun; Wang, Lin; Lakshminarayanan, Rajamani; Verma, Chandra; Wang, Yingjun; Tan, Donald; Cao, Derong; Beuerman, Roger W.; Ren, Li; Liu, Shouping*, Symmetrically Substituted Xanthone Amphiphiles Combat Gram-positive Bacterial Resistance with Enhanced Membrane Selectivity, J. Med. Chem. 2017 Feb 23; 60(4):1362-1378.

  4. Koh JJ, Zou H, Lin S, Lin H, Soh RT, Lim FH, Koh WL, Li J, Lakshminarayanan R, Verma C, Tan DT, Cao D, Beuerman RW, Liu S.*, Nonpeptidic Amphiphilic Xanthone Derivatives: Structure-Activity Relationship and Membrane-Targeting Properties. J. Med. Chem. 2016 Jan 14;59(1):171-93.

  5. Koh JJ, Lin H, Caroline V, Chew YS, Pang LM, Aung TT, Li J, Lakshminarayanan R, Tan DT, Verma C, Tan AL, Beuerman RW, Liu S.*, N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. J. Med. Chem. 2015 Aug 27;58(16):6533-48.

  6. Koh JJ, Lin S, Aung TT, Lim F, Zou H, Bai Y, Li J, Lin H, Pang LM, Koh WL, Salleh SM, Lakshminarayanan R, Zhou L, Qiu S, Pervushin K, Verma C, Tan DT, Cao D, Liu S*, Beuerman RW., Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections, J Med Chem. 2015 Jan 22;58(2):739-52

  7. Zou H, Koh JJ, Li J, Qiu S, Aung TT, Lin H, Lakshminarayanan R, Dai X, Tang C, Lim FH, Zhou L, Tan AL, Verma C, Tan DT, Chan HS, Saraswathi P, Cao D, Liu S*, Beuerman RW, Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity. J Med Chem. 2013 Mar 28;56(6):2359-73.

    联系邮箱:liusp@gzhmu.edu.cn; liushouping2018@163.com