【个人简介】
罗会龙,南山学者,广州医科大学特聘教授。2019年获得巴黎第五大学药学博士学位,随后分别于美国威斯康星大学麦迪逊分校和上海交通大学医学院从事博士后研究;2023年底任上海交通大学医学院副研究员(副高);2024年8月加入广州医科大学药学院-临床药学系。主要从事基于创新菌种的活体药物体内定量调控及工程化改造,致力于解决活体生物药临床转化及产业化的瓶颈问题,推动其在治疗领域的应用。近年来,以第一作者或通讯作者在Nature Communications(2篇)、Science Advances、Materials Today、Pharmacological Research等期刊发表10余篇研究论文(其中6篇IF>10),授权欧洲发明专利1项,申请中国发明专利2项。担任iMeta(IF=23.8)、Food & Medicine Homology等多个杂志编委/青年编委。目前主持国家自然科学基金青年项目1 项,教育部海外博士引进项目 1 项,中国博士后科学基金面上项目1项,并获得广州医科大学“高水平大学建设项目”引进高层次人才科研启动项目资助。
【联系邮箱】
huilongluo@gzhmu.edu.cn
【研究方向】
1. 基于临床转化的活体药物工程化改造与应用;
2. 活体药物体内过程及其定量调控;
3. 药物与生理屏障相互作用机制及相关临床药理研究;
【主要科研项目】
1. 广州医科大学“高水平大学建设项目”引进高层次人才科研启动项目,2024-2029,承担经费:300万,主持。
2. 教育部海外引才专项,2021-2023,承担经费:60万,主持。
3. 国家自然科学基金青年基金项目,2023-2024,承担经费:20万,主持。
4. 国家博士后科学基金第71批面上资助项目,2021-2023,承担经费:8万,主持。
5. 美国国立卫生研究院NIH资助项目(R01 NS099158),2017-2022,项目经费:1157万,参与。
【代表性论文】
1. Yu W, Luo H# (Co-first author), Han B, Lin S, Li Q, Xue R, Tang H, Jia X*, Wang L*, and Liu J*. Restoring mucosal barrier homeostasis by in situ formation of a living-synthetic therapeutic coating. Nature Communications. 2025.
2. Wu F, Lin S, Luo H# (Co-first author), Wang C, Liu J*, Zhu X* and Pan Y*. Noncontact microbiota transplantation by core-shell microgel-enabled nonleakage envelopment. Science Advances. 2025; 11, 6.
3. Luo H, Chen Y, Kuang X, Wang X, Yang F, Cao Z, Wang L, Lin S, Wu F, and Liu J*. Chemical reaction-mediated covalent localization of bacteria. Nature Communications. 2022; 13, 7808.
4. Luo H, Wu F, Wang X, Lin S, Zhang M, Cao Z*, and Liu J*. Encoding bacterial colonization and therapeutic modality by wrapping with an adhesive drug-loadable nanocoating. Materials Today. 2023; 62, 98.
5. Luo H, Xie J, Su X, Lin S, Chen H*, Kuang X*, and Liu J*. Tannic acid-based metal-phenolic networks as a versatile platform to mediate cell therapy. Science China Materials. 2024. 67, 3833-3848.
6. Luo H, Lucie C, Frank B, Bruno M, Bruno E, Cisternino S, Declèves X*. The role of brain barriers in the neurokinetics and pharmacodynamics of lithium. Pharmacological Research. 2021; 166:105480.
7. Hejin Jiang, Rui Liu, Ying Liu, Luo H*(Co-corresponding author), Zhenping Cao*, Jinyao Liu*. Chiral coating-mediated interactions of bacteria with diverse biointerfaces. Science China Chemistry. 2023; 66: 3594-3601.
8. Chen Y, Lin S, Wang L, Zhang Y, Chen H, Fu Z, Zhang M, Luo H, and Liu J*. Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria. Nature Biomedical Engineering. 2024; 8(7).
9. Luo H, Frank B, Bruno M, Cisternino S, and Declèves X*. Molecular and functional study of transient receptor potential vanilloid 1-4 (TRPV1-4) at the rat and human blood-brain barrier reveals interspecies differences. Frontiers in Cell and Developmental Biology. 2020;8: 578514.
10. Luo H, Declèves X, and Cisternino S*. Transient Receptor Potential Vanilloid in the Brain Gliovascular Unit: Prospective Targets in Therapy. Pharmaceutics. 2021; 13(3): 334.
11. Luo H, and Eric Shusta*. Blood-brain barrier modulation to improve glioma drug delivery. Pharmaceutics. 2020; 12(11): 1085.
12. Luo H, Elisa R, Bruno S, Stephanie C, Veronique C, Nina C, Maria S, Fabienne G, Nicolas P, Sandrine B, David M. S, Marie-Claude M, Pierre-Olivier C, Cisternino S, Declèves X*. Cannabidiol Increases Proliferation, Migration, Tubulogenesis, and Integrity of Human Brain Endothelial Cells through TRPV2 Activation. Molecular Pharmaceutics. 2019; 16, 3: 1312.
13. Luo H, Gauthier M, Landry C, Poupon J, Dehouck M, Gosselet F, Perrière N, Cisternino S, Declèves X*. Sodium transporters are involved in lithium influx in brain endothelial cells. Molecular Pharmaceutics. 2018; 15, 7: 2528-2538.
14. Luo H, Zhong J, Ye F, Wang Q, Ma Y*, Liu P, Zhang H, Sun M, Jiang J. A systematic quality control method of Huangqi decoction: simultaneous determination of eleven flavonoids and seven triterpenoid saponins by UHPLC-MS. Analytical Methods, 2014; 6: 4593.