【个人简介】

黄玉刚，教授，研究生导师，广州市高层次人才。2012-至今在广州医科大学药学院工作，主要研究领域为智能高分子递药载体系统的设计、制备及应用。以第一或通讯作者身份在ACS Macro Letters, Chemistry of Materials, Chem. Commun等期刊发表SCI论文30余篇，授权发明专利3项，主持包括NSFC基金在内的各类基金6项。作为主要成员获得2020年广东省科技进步奖一等奖、2024广东医学科技奖、2021广东省药理学会科技成果奖各一项。

教育经历：

2001.09-2005.06， 郑州大学，高分子材料与工程，学士；

2005.09-2008.06，华南理工大学，材料学，硕士；

2008.09-2011.06， 中山大学，高分子化学与物理， 博士。

【联系邮箱】

hyug@gzhmu.edu.cn

【研究方向类别】

1、学术学位：药剂学

2、专业学位：工业药学（转化药学）

【具体研究方向】  

药物靶向递送高分子载体；生物医用高分子材料

【主要科研项目】

1、主持国家自然科学基金青年项目(51403043)，具有生物功能性的多肽基纳米载体系统的构建及二级结构的基础作用研究，已结题。

2、企业横向项目：医用抗凝血聚氨酯材料的研究与开发，在研。

【所获荣誉和奖励】

2020广东省科技进步奖一等奖、2024广东医学科技奖二等奖、2021广东省药理学会科技成果奖二等奖。

【主要论文及著作（代表性）】

1) Xujun Lu, Jiajian Qiu, Yilan Li, Ming Cai, Xiaohan Yang, Suifei Li, Guodong Ye, Wei Yi* and Yugang Huang*. PEGylation can effectively strike a balance in siRNA delivery performances of guanidinylated linear synthetic polypeptides with potential use for transcriptional gene silencing. ACS Macro Letters, 2024, 13, 1251–1257.

2) Yilan Li, Jianlun Zhong, Xujun Lu, Ming Cai, Haoyuan Zhu, Guodong Ye, Wei Yi*, Chuanshan Xu* and Yugang Huang*. Preparation of tumor-targeting pH-Sensitive polymeric nanoprodrugs through the self-assembly of biotinylated polymer–drug conjugates utilizing a simple Diels–Alder chemical strategy. Chemistry of Materials. 2024, 36, 20, 10142–10153.

3) Yandan Zhang, Qin Tang, Ming Cai, Jiating Cai, Suifei Li, Xingmei Deng, Lingran Du, Guodong Ye, Chuanshan Xu, Yugang Huang*. A simple and efficient strategy for preparing anticoagulant coatings on biomedical polyurethane surfaces through a fluorinated urethane prepolymer. Progress in Organic Coatings, 2024, 191, 108421.

4) Yandan Zhang, Jing Zhao, Jiating Cai, Xiujuan Ai, Peiquan Zhang, Huawen Hu, Chuanshan Xu, Minghui He, Guodong Ye, Yugang Huang*. Synthesis, UV-curing behaviors and general properties of acrylate-urethane resins prepared from castor oil-based polyols. Progress in Organic Coatings, 2024, 188, 108204.

5) Yugang Huang, Huanyan Liao, Runsheng Huang, Lijiang Huang, Gang Xie, Huawen Hu, Jianwen Yang.* Bis(trimethylsilyl)amino modified Type II photoinitiators can alleviate oxygen inhibition of near-UV LED photopolymerization due to moisture induced decomposition of initiators. European Polymer Journal, 2022, 172, 111236.

6) Junyang Zhong, Yusi Quan, Xiaoya Zhao, Suifei Li, Ziqing He, Guodong Ye, Mingna Sun, Yingling Miao, Chunping Ma, Huikang Yang, Xing Chen, Yugang Huang*. Coassembling functionalized glycopolypeptides to prepare pH-responsive self-indicating nanocomplexes to manipulate selfassembly/drug delivery and visualize intracellular drug release. Biomaterials Advances, 2022, 134, 112711.

7) Xinlin Jiang, Jijun Fu, Junyang Zhong, Xin Li, He Wang, Songjing Zhong, Yinhui Wei, Xiaoya Zhao, Xing Chen, Yi Zhou, Lingran Du, Guodong Ye, Jing Zhao, Yugang Huang.* Guanidinylated cyclic synthetic polypeptides can effectively deliver siRNA by mimicking the biofunctions of both cell-penetrating peptides and nuclear localization signal peptides, ACS Macro Letters, 2021, 10, 767-773.

8) Xueyuan Chen, Junyang Zhong, Xinlin Jiang, Ziqing He, Yusi Quan, Songjing Zhong, Guangji Li,* Yugang Huang.* Structure and oxidation effects on conformation and thermoresponsiveness of the OEGylated poly(glutamic acid)- bearing side-chain thioether linkers. Langmuir, 2021, 37, 1288-1296.