何菊云-广州医科大学药学院

何菊云，女，博士，讲师，2009年获南华大学理学学士学位（生物技术专业）；2013年前往挪威国家营养与海洋食品研究所进行博士联合培养，并于2014年底回国获中山大学理学博士学位（水生生物学专业）；2015年加入赢创（中国）投资有限公司广州分公司担任北亚区水产研发与技术负责人；2023年加入广州医科大学药学院，从事教学与科研至今。主要研究方向包括营养素（蛋氨酸/二肽、赖氨酸、藻油等）对动物生长、摄食、健康及代谢的调控机制；围绕肠道健康与安全养殖，开发并研究适用于不同养殖环境的新型微生态制剂；基于中药资源产业过程副产物的研究、开发与利用。近年来在国内外动物营养领域发表学术论文超过25篇，其中以第一作者或通讯作者在Fish and Shellfish Immunology，Animal Nutrition，Aquaculture等国际知名期刊发表论文12篇。

【联系方式】

QQ：282780324

邮箱：hejuyun0719@163.com

【研究方向】

1、动物营养与健康

2、基于中药资源产业过程副产物的研究、开发与利用

【代表性研究论文】

1. He, J.Y., Tian, L.X., Lemme, A., Gao, W., Yang, H.J., Niu, J., Liang, G.Y., Chen, P.F., Liu, Y.J. Methionine and lysine requirements for maintenance and efficiency of utilization for growth of two sizes of tilapia (Oreochromis niloticus). Aquac. Nutr. 2013, 19(4), 629-640.

2. Holen E, He J.Y., Espe M, Chen L.Q, Araujo P. Combining eicosapentaenoic acid, decosahexaenoic acid and arachidonic acid, using a fully crossed design, affect gene expression and eicosanoid secretion in salmon head kidney cells in vitro. Fish Shellfish Immunol. 2015, 45(2): 695-703.

3. Holen E, He J.Y., Araujo P, Seliussen J, Espe M. Hydrolyzed fish proteins modulates both inflammatory and antioxidant gene expression as well as protein expression in a co culture model of liver and head kidney cells isolated from Atlantic salmon (Salmo salar). Fish Shellfish Immunol. 2016, 54: 22-9.

4. He, J.Y., Han, B., Tian, L.X., Yang, H.J., Zeng, S.L., Liu, Y.J. The sparing effect of cystine on methionine at a constant TSAA level in practical diets of juvenile Nile tilapia (Oreochromis niloticus). Aquac. Res. 2016, 47(7): 2031-2039.

5. He, J.Y., Long, W.Q., Han, B., Tian, L.X., Yang, H.J., Zeng, S.L., Liu, Y.J. Effect of dietary L-methionine concentrations on growth performance, serum immune and antioxidative responses of juvenile Nile tilapia, Oreochromis niloticus. Aquac. Res. 2017, 48(2): 665-674.

6. He, J.Y., Tian, L.X., Lemme, A., Gao, W., Yang, H.J., Han, B., Zeng, S.L., Liu, Y.J. The effect of dietary methionine concentration on growth performance of juvenile Nile tilapia (Oreochromis niloticus) fed diets with two different digestible energy levels. Aquac. Nutr. 2017, 23(1): 76-89.

7. Niu, J.^#, Lemme, A., He, J.Y^#., Li, H.Y., Xie, S.H., Liu, Y.J., Yang, H.J., Figueiredo-Silva, C., Tian L.X. Assessing the bioavailability of the Novel Met-Met product (AQUAVI^® Met-Met) compared to DL-Methionine (DL-Met) in white shrimp (Litopenaeus vannamei). Aquaculture. 2018, 484: 322-332. (^#共同第一作者)

8. Xie, J.J.^#, Lemme, A., He, J.Y.^#, Yin, P., Figueiredo-Silva, C., Liu, Y.J., Xie, S.H., Niu, J., Tian L.X. Fish meal levels can be successfully reduced in white shrimp (Litopenaeus vannamei) if supplemented with DL-Methionine (DL-Met) or DL-Methionyl-DL-Methionine (Met-Met). Aquac. Nutr. 2018, 24(3): 1144–1152. (^#共同第一作者)

9. Ji, K.^#, He, J.Y^#, Liang, H.L., Ren, M.C., Ge, X.-P., Masagounder, K. Response of gibel carp (Carassius auratus gibelio) to increasing levels of dietary lysine in zero fish meal diets. Aquac. Nutr. 2021, 27(1), 49-62. (^#共同第一作者)

10. Zhou, Y.Y.^#, He, J.Y^#, Su, N.N., Masagounder, K., Xu, M.L., Chen, L.L., Liu, Q.Y., Sun, Z.Z., Ye, C.X. Effects of DL-methionine and a methionine hydroxy analogue (MHA-Ca) on growth, amino acid profiles and the expression of genes related to taurine and protein synthesis in common carp (Cyprinus carpio). Aquaculture. 2021, 532, 735962. (^#共同第一作者)

11. Tao, X.Y.^#, He, J.Y^#, Lu, J.J., Chen, Z.J., Jin, M., Jiao, L.F., Masagounder, K., Liu, W.J., Zhou, Q.C. Effects of Bacillus subtilis DSM 32315 (Gutcare^®) on the growth performance, antioxidant status, immune ability and intestinal function for juvenile Litopenaeus vannamei fed with high/low-fishmeal diets. Aquac. Rep. 2022, 26: 101282. (^#共同第一作者)

12. Xie S.W., He J.Y*., Masagounder K., Liu Y.J., Tian LX., Tan B.P., Niu J*. Dietary lysine levels modulate the lipid metabolism, mitochondrial biogenesis and immune response of grass carp, Ctenopharyngodon idellus. ANIM FEED SCI TECH. 2022 (291):115373. (*共同通讯作者)

13. Liao Z.H., Liu Y.T., Wei H.L., He X.S., Wang Z.Q., Zhuang Z.X., Zhao W., Masagounder K., He J.Y*., Niu J*. Effects of dietary supplementation of Bacillus subtilis DSM 32315 on the growth, immune responses and acute ammonia stress tolerance of Nile tilapia (Oreochromis niloticus) fed with high or low protein diets. Anim Nutr. 2023 (accepted). (*共同通讯作者)

14. Wu M.L., He J.Y^#., Masagounder K., Huang F., Liang H.W., Dong L.X., Wen H., Jiang M., Lu X., Su S.Y., Tian J. Optimal DL-Methionyl-DL-Methionine supplementation in a plant-protein diet for red swamp crayfish Procambarus clarkii. AQUACULT INT. 2023 (accepted). (^#共同第一作者)