个人简介

余睿，男，博士，四川成都人。博士毕业于法国蒙彼利埃大学-法国国家科研中心-欧洲膜研究所，师从高分子化学家Suming Li 教授，动态组分化学家Mihail Barboiu 教授。2022年加入广州医科大学药学院，从事教学科研工作。现主持广州市科技项目、广州医科大学科研处-科研能力提升项目等，参与国家自然科学基金-面上项目一项，参与广东省教育厅重点科研平台和项目一项。研究方向聚焦于动态水凝胶材料制备及其生物医学应用开发，纳米复合材料的设计、制备与抗肿瘤机制研究。研究成果以第一/通讯作者在国际核心期刊Materials Science and Engineering C、Carbohydrate Polymers、International Journal of Pharmaceutics、Applied Surface Science、Catalysis Science & Technology、Chinese Chemical Letters等 SCI刊物发表相关学术论文十余篇。

联系方式

yurui@gzhmu.edu.cn ；rui_yu91@163.com

教育经历

2017.10-2021.06            蒙彼利埃大学                博士                                  2014.09-2017.06              四川大学                  硕士

2010.09-2014.06              四川大学                  学士

工作经历

2022.01 至今             广州医科大学药学院           讲师

科研方向

动态水凝胶材料设计及其生物医学应用开发；纳米复合材料（聚合药物等）的设计、制备及其抗肿瘤机制研究

主持/参与科研项目

1. 广州市科技局-一般项目，2023.04-2024.03，在研，主持

2. 广州医科大学科研能力提升项目，2023.01-2024.12，在研，主持

3. 广东省教育厅重点科研平台和项目，2022，在研，参与

4. 国家自然科学基金-面上项目，2024.01-2026.12，在研，参与

奖励和荣誉

2017.10-2021-06 国家留学基金委公派博士生项目

2016.12-2017.06 研究生国家奖学金，优秀毕业生

讲授课程

《基础化学》、《有机化学》

主要代表性论文及著作（* 通讯作者）

1. C. Zhang, H. Zhong, X. Li, Z. Xing, J. Liu, R. Yu *, X. Deng * (2023) Design, synthesis and bioactivity investigation of peptide-camptothecin conjugates as anticancer agents with a potential to overcome drug resistance. International Journal of Pharmaceutics:123402. (IF = 5.8)

2. R. Yu, S. Li *, Synthesis, Properties, and Applications of Carboxymethyl Chitosan-Based Hydrogels, Advances in polymer science, (2023). (IF = 10.125)

3. C. Zhang, X. Li, Z. Xing, H. Zhong, D. Yu, R. Yu *, X. Deng * (2023) Plasma metabolites-based design of long-acting peptides and their anticancer evaluation. International journal of pharmaceutics 631:122483-122483. (IF = 5.8)

4. R. Yu, E. Petit, M. Barboiu *, S. Li *, W. Sun *, C. Chen (2021) Biobased dynamic hydrogels by reversible imine bonding for controlled release of thymopentin. Materials Science and Engineering: C 127:112210. (IF = 7.328)

5. R. Yu, Y. Zhang, M. Barboiu *, M. Maumus, D. Noël *, C. Jorgensen, S. Li * (2020) Biobased pH-responsive and self-healing hydrogels prepared from O-carboxymethyl chitosan and a 3-dimensional dynamer as cartilage engineering scaffold. Carbohydrate Polymers 244:116471. (IF = 11.2)

6. R. Yu, L. Cornette de Saint-Cyr, L. Soussan, M. Barboiu *, S. Li * (2020) Anti-bacterial dynamic hydrogels prepared from O-carboxymethyl chitosan by dual imine bond crosslinking for biomedical applications. International Journal of Biological Macromolecules 167:1146-1155. (IF = 8.2)

7. Y. Zhang, C. Pham, R. Yu, E. Petit, S. Li *, M. Barboiu * (2020) Dynamic hydrogels based on double imine connections and application for delivery of fluorouracil. Frontiers in Chemistry 8:739. (IF = 5.5)

8. R. Yu, R. Liu, J. Deng, M. Ran, N. Wang, W. Chu, Z. He, Z. Du, C. Jiang *, W. Sun *, Pd nanoparticles immobilized on carbon nanotubes with a polyaniline coaxial coating for the Heck reaction: coating thickness as the key factor influencing the efficiency and stability of the catalyst, Catalysis Science & Technology 8(5) (2018) 1423-1434. (IF = 6.1)

9. R. Yu, C. Jiang, W. Chu, M. Ran *, W. Sun *, Decoration of CNTs’ surface by Fe₃O₄ nanoparticles: Influence of ultrasonication time on the magnetic and structural properties, Chinese Chemical Letters 28(2) (2017) 302-306. (IF = 9.1)

10. R. Yu, C. Jiang, W. Chu, J. Zhao, W. Sun *, M. Ran *, Sonochemical synthesis of magnetic properties of Fe3O4/CNT nanocomposites, Integrated Ferroelectrics 179(1) (2017) 77-83.

11. R. Yu, M. Ran, J. Wen *, W. Sun, W. Chu, C. Jiang, Z. He *, The effect of hydroxylation on CNT to form Chitosan-CNT composites: A DFT study, Applied Surface Science 359 (2015) 643-650. (IF = 6.7)